Active ingredients and safety of Sasa extract
We have summarized the active ingredients, superiority, and safety of our Sasa extract and LIOHERBAL™. We use our own manufacturing method to extract active ingredients such as polyphenols and polysaccharides from Hokkaido kumazasa to a high concentration without destroying them, and we have confirmed that it is highly safe to use in food and cosmetics.
Active ingredients in Sasa extract
It contains a lot of "xylooligosaccharide" which is a steam-decomposed product of hemicellulose contained in Kumazasa. Other organic acids, polyphenols, etc. are abundantly extracted.
Figure 1: GC-MS chromatogram
Figure 2: Sugar analysis chromatogram
Advantages of steam extraction method
Aiming to extract as much of the rare "xylo-oligosaccharide" contained in Kumazasa as possible, we have conducted repeated research by applying the natural pigment extraction and purification technology we have cultivated over the years. Based on various extraction experiments and theories, we invented the "steaming extraction method" and succeeded in mass production. (Patent No. 3983233)
Safety of Sasa Extract
residual pesticides
No positive list 360 pesticides found in the leaves used.
Analysis agency: Hokkaido Air Water Co., Ltd. Environmental Analysis Center
Safety test
Acute toxicity test (LD50) is >5,000mg/kg, ensuring high safety.
In addition, there are no problems with all safety test items required for cosmetics.
| Test items | result | Ministry of Health, Labor and Welfare guidelines | |
|---|---|---|---|
| healthy food | Cosmetic products | ||
| Single dose toxicity (acute toxicity) | ＞5,000mg/kg | ○ | ○ |
| Reverse mutation test (Ames method) | negative | ○ | ○ |
| 90-day repeated dose study | NOAEL 5,000mg/kg/day | ○ | － |
| Chromosomal abnormality test | negative | ○ | ○ |
| phototoxicity | negative | － | ○ |
| photosensitivity | negative | － | ○ |
| Primary skin irritation | negative | － | ○ |
| 2 weeks continuous skin irritation | negative | － | ○ |
| Skin sensitization | negative | － | ○ |
| Ocular mucosal irritation | Very mild irritation at 100% concentration | － | ○ |
| total pheophorbide | Not detected | － | － |
| Heavy metals (as Pb) | ＜20ppm | － | － |
| Arsenic (as As2O3) | ＜2ppm | － | － |
*Test substance: Sasa extract manufactured by TOYOCHEM CO., LTD.
*Testing organization: Biotoxtech, Japan Food Research Center
*GLP:OECD Principles of Good Laboratory Practice (as revised in 1997)
*Guidelines: Compliant with Ministry of Health, Labor and Welfare guidelines
Inquiries
TOYOCHEM CO., LTD. L&H Business Promotion Department
TEL:+81-3-3272-0902